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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2001-5-9
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pubmed:abstractText |
Significant advances have been made in elucidating the biogenesis pathway and three-dimensional structure of the UsnRNPs, the building blocks of the spliceosome. U2 and U4/U6*U5 tri-snRNPs functionally associate with the pre-mRNA at an earlier stage of spliceosome assembly than previously thought, and additional evidence supporting UsnRNA-mediated catalysis of pre-mRNA splicing has been presented.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0955-0674
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
290-301
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11343899-Animals,
pubmed-meshheading:11343899-Crystallography,
pubmed-meshheading:11343899-Humans,
pubmed-meshheading:11343899-Macromolecular Substances,
pubmed-meshheading:11343899-Protein Structure, Tertiary,
pubmed-meshheading:11343899-Protein Transport,
pubmed-meshheading:11343899-RNA, Small Nuclear,
pubmed-meshheading:11343899-RNA Splicing,
pubmed-meshheading:11343899-Ribonucleoprotein, U1 Small Nuclear,
pubmed-meshheading:11343899-Ribonucleoproteins, Small Nuclear,
pubmed-meshheading:11343899-Spliceosomes
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pubmed:year |
2001
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pubmed:articleTitle |
Spliceosomal UsnRNP biogenesis, structure and function.
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pubmed:affiliation |
Max Planck Institute of Biophysical Chemistry, Department of Cellular Biochemistry, Am Fassberg 11, 37077 Göttingen, Germany. cwill1@gwdg.de
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
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