Linked Life Data

11343372

Source:http://linkedlifedata.com/resource/pubmed/id/11343372

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9-10
pubmed:dateCreated
2001-5-8
pubmed:abstractText
A generalized estimating equation (GEE) approach is used to estimate the sensitivity and specificity of five non-culture screening tests for detecting Chlamydia trachomatis in endocervical specimens from women attending family planning clinics. Since the estimates of these parameters can be very close to the upper limit of one, confidence interval construction based on the traditional approaches, such as the delta method or a back-transformation approach, may not have the stated coverage. We compare different approaches to calculating confidence intervals for the sensitivity and specificity from the results of the GEE approach. These methods include the delta method, a back-transformation approach, and a bootstrap approach. In addition, we use simulations to investigate the estimated coverage rates of the delta method and the back-transformation approach. Published in 2001 by John Wiley & Sons, Ltd.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0277-6715
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1529-39
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:articleTitle
A GEE approach to estimating sensitivity and specificity and coverage properties of the confidence intervals.
pubmed:affiliation
CDC, 1600 Clifton Road, Mailstop E-63, Atlanta, GA 30033, USA. mrs7@cdc.gov
pubmed:publicationType
Journal Article