Source:http://linkedlifedata.com/resource/pubmed/id/11342784
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2001-5-8
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pubmed:abstractText |
The cytogenetic findings for two epithelioid hemangioendotheliomas are reported. An identical chromosomal translocation involving chromosomes 1 and 3 [t(1;3)(p36.3;q25)] was detected in both cases of epithelioid hemangioendothelioma, possibly representing a characteristic rearrangement for this histopathologic entity. The presence of clonal karyotypic abnormalities supports a neoplastic origin for the epithelioid variant of hemangioendothelioma. Identification of the 1;3 translocation may be useful diagnostically. Should additional studies confirm these data, this could lead to the identification of the gene(s) central to this neoplastic process.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0147-5185
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
684-7
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:11342784-Adult,
pubmed-meshheading:11342784-Antigens, CD31,
pubmed-meshheading:11342784-Chromosomes, Human, Pair 1,
pubmed-meshheading:11342784-Chromosomes, Human, Pair 3,
pubmed-meshheading:11342784-Clone Cells,
pubmed-meshheading:11342784-Female,
pubmed-meshheading:11342784-Hemangioendothelioma, Epithelioid,
pubmed-meshheading:11342784-Humans,
pubmed-meshheading:11342784-Immunohistochemistry,
pubmed-meshheading:11342784-Karyotyping,
pubmed-meshheading:11342784-Liver Neoplasms,
pubmed-meshheading:11342784-Middle Aged,
pubmed-meshheading:11342784-Neoplasm Proteins,
pubmed-meshheading:11342784-Soft Tissue Neoplasms,
pubmed-meshheading:11342784-Translocation, Genetic,
pubmed-meshheading:11342784-Tumor Markers, Biological
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pubmed:year |
2001
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pubmed:articleTitle |
Translocation t(1;3)(p36.3;q25) is a nonrandom aberration in epithelioid hemangioendothelioma.
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pubmed:affiliation |
Departments of Pathology & Microbiology, University of Nebraska Medical Center, Omaha, Nebraska 68198-3135, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Case Reports,
Research Support, Non-U.S. Gov't
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