Source:http://linkedlifedata.com/resource/pubmed/id/11342325
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3-4
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pubmed:dateCreated |
2001-5-8
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pubmed:abstractText |
A 47-year-old female with idiopathic myelofibrosis developed isolated granulocytic sarcoma with der (1; 7)(q10; p10) after splenectomy, followed by acute myelogenous leukemia. The patient had myelofibrosis since 22 years of age, received splenectomy at 47 years, and developed isolated submandibular granulocytic sarcoma, 8 months later. Although the initial tumor disappeared after irradiation, recurrent tumors selectively appeared in the areas of operative scars. She subsequently developed blastic transformation with der (1; 7)(q10; p10), and the blasts were refractory to different chemotherapy. This case is very rare in the following aspects: the onset of myelofibrosis occurred at a relatively young age; isolated granulocytic sarcoma after splenectomy preceded the transformation to acute leukemia; and the subcutaneous tumors developed in areas of operative scars.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1042-8194
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
427-33
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:11342325-Chromosomes, Human, Pair 1,
pubmed-meshheading:11342325-Chromosomes, Human, Pair 7,
pubmed-meshheading:11342325-Cicatrix,
pubmed-meshheading:11342325-Disease Progression,
pubmed-meshheading:11342325-Female,
pubmed-meshheading:11342325-Humans,
pubmed-meshheading:11342325-Leukemia, Myeloid,
pubmed-meshheading:11342325-Leukemia, Myeloid, Acute,
pubmed-meshheading:11342325-Mandibular Neoplasms,
pubmed-meshheading:11342325-Middle Aged,
pubmed-meshheading:11342325-Primary Myelofibrosis,
pubmed-meshheading:11342325-Skin Neoplasms,
pubmed-meshheading:11342325-Splenectomy,
pubmed-meshheading:11342325-Translocation, Genetic
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pubmed:year |
2000
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pubmed:articleTitle |
Idiopathic myelofibrosis developing isolated granulocytic sarcoma with der (1;7)(q10; p10) after splenectomy and finally transforming to acute myelogenous leukemia.
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pubmed:affiliation |
First Department of Internal Medicine, Gifu University School of Medicine, 40 Tsukasa-machi, Gifu 500-8705, Japan.
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pubmed:publicationType |
Journal Article,
Case Reports
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