Linked Life Data

11342288

Source:http://linkedlifedata.com/resource/pubmed/id/11342288

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2001-5-8
pubmed:abstractText
Resolution of synthetic racemic pterocarpans was achieved by CD monitored HPLC using a chiral stationary phase. No sign of exciton coupling was seen in the CD spectra of the pterocarpan enantiomers. The predominance of the chromane chromophore was indicated by the high intensity of the (1) L(b) band. The chirality of both the chromane and dihydrobenzo[b]furane chromophores was found to be governed by the second chiral sphere. An oxygen atom in pseudoaxial position at the benzylic atom of the chroman ring system gave rise to an increased third-sphere contribution and the positive sign of the (1) L(b) and negative sign of the (1) L(a) band. This resulted in a general positive-negative-negative sign pattern of the (1) L(b), (1) L(a) and (1) B(b) bands of the second-eluted enantiomer of P helicity suggesting homochirality and the same absolute configuration of the chiral centers.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1024-2430
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
535-43
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Determination of the absolute configuration of synthetic pterocarpans by chiral HPLC using on-line CD detection.
pubmed:affiliation
Department of Organic Chemistry, Eötvös Loránd University P.O. Box 32, H-1518 Budapest 112, Hungary.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't