Source:http://linkedlifedata.com/resource/pubmed/id/11330569
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2001-5-1
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pubmed:abstractText |
The bioincompatibility of peritoneal dialysis fluids (PDF) in current use has been partially attributed to the presence of glucose degradation products (GDPs), which are generated during heat sterilization of PDF. Several of the GDPs have been identified and we have recently demonstrated that these GDPs per se may impair the viability and function of human peritoneal mesothelial cells (HPMC) in vitro. It is also possible that GDP-related toxicity is further exacerbated by the milieu of PDF. We review the current literature on GDP and present the results of experiments comparing the impact of heat- and filter-sterilized PDF on the viability and function of HPMC.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0896-8608
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
201-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11330569-Animals,
pubmed-meshheading:11330569-Cell Survival,
pubmed-meshheading:11330569-Cells, Cultured,
pubmed-meshheading:11330569-Chemokine CCL2,
pubmed-meshheading:11330569-Dialysis Solutions,
pubmed-meshheading:11330569-Epithelial Cells,
pubmed-meshheading:11330569-Glucose,
pubmed-meshheading:11330569-Glycosylation End Products, Advanced,
pubmed-meshheading:11330569-Humans,
pubmed-meshheading:11330569-Peritoneal Dialysis, Continuous Ambulatory,
pubmed-meshheading:11330569-Peritoneum,
pubmed-meshheading:11330569-Sterilization
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pubmed:articleTitle |
Glucose degradation products and peritoneal membrane function.
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pubmed:affiliation |
Department of Nephrology and Medical Intensive Care, Universitätsklinikum Charité, Medizinische Fakultät der Humboldt-Universität zu Berlin, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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