Source:http://linkedlifedata.com/resource/pubmed/id/11330365
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
2001-5-1
|
pubmed:abstractText |
One hundred fifty-one female patients with acute urethral syndrome caused by Chlamydia trachomatis were examined. First, patients were divided into two groups, those with clinical symptoms present < 3 weeks before the start of treatment, and those with clinical symptoms > or = 3 weeks prior to the beginning of therapy. Then patients were further divided into groups and randomized to receive azithromycin once daily in a single dose of 1.0 g or 500 mg once daily for 6 days, or to receive doxycycline 100 mg b.i.d. for 14 days or 100 mg b.i.d. for 7 days (8 study groups in all). Clinical and bacteriological efficacy was evaluated 3 weeks after the end of therapy. In the group of patients with disease symptoms lasting for 3 weeks or longer, the eradication and clinical cure rates were significantly higher after administration of azithromycin in a dose of 1x500 mg/6 days than after a single dose of 1.0 g (p<0.01), and after administration of doxycycline 2x100 mg/14 days than by using doxycycline 2x100 mg/7 days (p<0.05).
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
1120-009X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
13
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
176-81
|
pubmed:dateRevised |
2009-8-4
|
pubmed:meshHeading |
pubmed-meshheading:11330365-Administration, Oral,
pubmed-meshheading:11330365-Adolescent,
pubmed-meshheading:11330365-Adult,
pubmed-meshheading:11330365-Aged,
pubmed-meshheading:11330365-Anti-Bacterial Agents,
pubmed-meshheading:11330365-Azithromycin,
pubmed-meshheading:11330365-Chlamydia Infections,
pubmed-meshheading:11330365-Chlamydia trachomatis,
pubmed-meshheading:11330365-Dose-Response Relationship, Drug,
pubmed-meshheading:11330365-Doxycycline,
pubmed-meshheading:11330365-Drug Administration Schedule,
pubmed-meshheading:11330365-Female,
pubmed-meshheading:11330365-Humans,
pubmed-meshheading:11330365-Middle Aged,
pubmed-meshheading:11330365-Syndrome,
pubmed-meshheading:11330365-Treatment Outcome,
pubmed-meshheading:11330365-Urethral Diseases
|
pubmed:year |
2001
|
pubmed:articleTitle |
Duration of clinical symptoms in female patients with acute urethral syndrome caused by Chlamydia trachomatis treated with azithromycin or doxycycline.
|
pubmed:affiliation |
University Hospital for Infectious Diseases Dr. Fran Mihaljevi?, Zagreb, Croatia. bfm@fran.bfm.hr
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|