Source:http://linkedlifedata.com/resource/pubmed/id/11328539
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
2001-4-30
|
pubmed:abstractText |
We present a case of intra-epithelial carcinoma occurring in a serrated adenoma of the colon. The pedunculated polyp, which measured 12 x 10 x 6 mm, was endoscopically removed from the ascending colon of a 78-year-old woman. Histologically, the polyp mainly consisted of serrated adenomatous glands, and had foci of intra-epithelial carcinoma at the top. Hyperplastic (metaplastic) areas were also present in both borders between the serrated adenomatous area and the surrounding normal mucosa. A sequential increase in the degree of dysplasia, and in the number of nuclei positively reactive for Ki-67 and p53 was evident from the hyperplastic areas toward the foci of carcinoma. The polyp described here may represent a carcinogenic potential of hyperplastic polyp via serrated adenoma.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
1320-5463
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
51
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
215-20
|
pubmed:dateRevised |
2005-11-17
|
pubmed:meshHeading |
pubmed-meshheading:11328539-Adenocarcinoma,
pubmed-meshheading:11328539-Adenoma,
pubmed-meshheading:11328539-Aged,
pubmed-meshheading:11328539-Colonic Polyps,
pubmed-meshheading:11328539-Colorectal Neoplasms,
pubmed-meshheading:11328539-Female,
pubmed-meshheading:11328539-Humans,
pubmed-meshheading:11328539-Immunohistochemistry,
pubmed-meshheading:11328539-Ki-67 Antigen,
pubmed-meshheading:11328539-Neoplasms, Multiple Primary,
pubmed-meshheading:11328539-Tumor Suppressor Protein p53
|
pubmed:year |
2001
|
pubmed:articleTitle |
Colonic intra-epithelial carcinoma occurring in a hyperplastic polyp via a serrated adenoma.
|
pubmed:affiliation |
Department of Pathology, Hirosaki University School of Medicine, 5 Zaifu-Cho, Hirosaki 036-8562, Japan. masa@cc.hirosaki-u.ac.jp
|
pubmed:publicationType |
Journal Article,
Case Reports
|