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11327595
Source:
http://linkedlifedata.com/resource/pubmed/id/11327595
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Statements in which the resource exists as a subject.
Predicate
Object
rdf:type
pubmed:Citation
lifeskim:mentions
umls-concept:C0018321
,
umls-concept:C0038477
,
umls-concept:C0220781
,
umls-concept:C0243071
,
umls-concept:C0243077
,
umls-concept:C0673071
,
umls-concept:C1883254
pubmed:issue
8
pubmed:dateCreated
2001-4-30
pubmed:abstractText
The synthesis of a novel series of guanine analogues is reported. The compounds have been assessed in vitro and some analogues have been found to be inhibitors of phosphodiesterase type 7 (PDE7).
pubmed:language
eng
pubmed:journal
http://linkedlifedata.com/resource/pubmed/journal/9107377
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/3',5'-Cyclic-AMP Phosphodiesterases
,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclic Nucleotide...
,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclic Nucleotide...
,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclic Nucleotide...
,
http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors
,
http://linkedlifedata.com/resource/pubmed/chemical/Guanine
,
http://linkedlifedata.com/resource/pubmed/chemical/Isoenzymes
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0960-894X
pubmed:author
pubmed-author:BarnesM JMJ
,
pubmed-author:CooperNN
,
pubmed-author:DavenportR JRJ
,
pubmed-author:DykeH JHJ
,
pubmed-author:GallewayF PFP
,
pubmed-author:GalvinF CFC
,
pubmed-author:GowersLL
,
pubmed-author:HaughanA FAF
,
pubmed-author:LoweCC
,
pubmed-author:MeissnerJ WJW
,
pubmed-author:MontanaJ GJG
,
pubmed-author:MorganTT
,
pubmed-author:PickenC LCL
,
pubmed-author:WatsonR JRJ
pubmed:issnType
Print
pubmed:day
23
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1081-3
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed-meshheading:11327595-3',5'-Cyclic-AMP Phosphodiesterases
,
pubmed-meshheading:11327595-Cyclic Nucleotide Phosphodiesterases, Type 3
,
pubmed-meshheading:11327595-Cyclic Nucleotide Phosphodiesterases, Type 4
,
pubmed-meshheading:11327595-Cyclic Nucleotide Phosphodiesterases, Type 7
,
pubmed-meshheading:11327595-Enzyme Inhibitors
,
pubmed-meshheading:11327595-Guanine
,
pubmed-meshheading:11327595-Inhibitory Concentration 50
,
pubmed-meshheading:11327595-Isoenzymes
,
pubmed-meshheading:11327595-Structure-Activity Relationship
pubmed:year
2001
pubmed:articleTitle
Synthesis and structure-activity relationships of guanine analogues as phosphodiesterase 7 (PDE7) inhibitors.
pubmed:affiliation
Celltech R & D, Granta Park, Great Abington, Cambridge, UK.
pubmed:publicationType
Journal Article