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pubmed-article:11325591pubmed:abstractTextGranzyme B, one of the most abundant granzymes in cytotoxic T-lymphocyte (CTL) granules, and members of the caspase (cysteine aspartyl proteinases) family have a unique cleavage specificity for aspartic acid in P1 and play critical roles in the biochemical events that culminate in cell death.lld:pubmed
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pubmed-article:11325591pubmed:articleTitleThe three-dimensional structure of human granzyme B compared to caspase-3, key mediators of cell death with cleavage specificity for aspartic acid in P1.lld:pubmed
pubmed-article:11325591pubmed:affiliationDepartment of Endocrinology and Chemical Biology, Merck Research Laboratories, Rahway, NJ 07065-0900, USA. rotonda@merck.comlld:pubmed
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