Linked Life Data

11324565

Source:http://linkedlifedata.com/resource/pubmed/id/11324565

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2001-4-27
pubmed:abstractText
Orphanin FQ (OFQ) is a newly-discovered neuropeptide which shares great similar sequence with endogenous opioid peptide but with different functions. The present study was to investigate the role of OFQ microinjected in the periaqueductal gray (PAG) on pain threshold and acupuncture analgesia (AA) using tail flick tests. The results show that the hyperalgesia of OFQ and its antagonization on AA in PAG are dose-related. OFQ in PAG decreases the enhancing effect on AA induced by ohmefentanyl, a selective mu-receptor agonist. These observations suggest that OFQ in PAG can increase the rat pain sensitivity and antagonize AA.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0371-0874
pubmed:author
pubmed:issnType
Print
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
263-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
[Effect of orphanin FQ on acupuncture analgesia and noxious stimulation in the periaqueductal gray].
pubmed:affiliation
State Key Laboratory of Neurobiology, Shanghai Medical University, Shanghai 200032.
pubmed:publicationType
Journal Article, English Abstract, Research Support, Non-U.S. Gov't