Linked Life Data

11320442

Source:http://linkedlifedata.com/resource/pubmed/id/11320442

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2001-4-26
pubmed:abstractText
Functional neuroimaging allows the non-invasive identification of distributed patterns of human brain activity associated with perceptual, congnitive, emotional and behavioral processes, in health and disease. Work in this field is methodologically intensive, requiring an interdisciplinary team of scientists to develop and apply rapidly advancing techniques. Here we focus upon the principles and methods of functional imaging, from hypothesis generation and study design, to subject recruitment and clinical characterization, neuropsychological paradigm development, image acquisition, image processing and statistical analysis, and data interpretation. The strengths and limitations of the various techniques are discussed, with an emphasis on positron emission tomography (PET) and functional magnetic resonance imaging (fMRI), which have proven to be powerful tools for human brain mapping. The integration of these techniques with electroencephalography (EEG) and magnetoencephalography (MEG), which provide greater temporal information, is outlined. An understanding of such methodological issues is a necessary prerequisite to the development of new imaging methods with improved capabilities, to the careful application of existing methods to neuropsychological problems, and to the critical examination of planned or published studies.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1380-3395
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3-18
pubmed:dateRevised
2008-4-14
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Advances in functional neuroimaging methodology for the study of brain systems underlying human neuropsychological function and dysfunction.
pubmed:affiliation
Functional Neuroimaging Laboratory, Department of Psychiatry, Weill Medical College of Cornell University, New York, NY, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review, Research Support, Non-U.S. Gov't