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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
17
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pubmed:dateCreated |
2001-4-12
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pubmed:abstractText |
Typhoid fever is common in developing countries. The licensed typhoid vaccines confer only about 70 percent immunity, do not protect young children, and are not used for routine vaccination. A newly devised conjugate of the capsular polysaccharide of Salmonella typhi, Vi, bound to nontoxic recombinant Pseudomonas aeruginosa exotoxin A (rEPA), has enhanced immunogenicity in adults and in children 5 to 14 years old and has elicited a booster response in children 2 to 4 years old.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/ADP Ribose Transferases,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Bacterial,
http://linkedlifedata.com/resource/pubmed/chemical/Bacterial Toxins,
http://linkedlifedata.com/resource/pubmed/chemical/Exotoxins,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin G,
http://linkedlifedata.com/resource/pubmed/chemical/Polysaccharides, Bacterial,
http://linkedlifedata.com/resource/pubmed/chemical/Typhoid-Paratyphoid Vaccines,
http://linkedlifedata.com/resource/pubmed/chemical/Vaccines, Conjugate,
http://linkedlifedata.com/resource/pubmed/chemical/Vi polysaccharide vaccine, typhoid,
http://linkedlifedata.com/resource/pubmed/chemical/Virulence Factors,
http://linkedlifedata.com/resource/pubmed/chemical/toxA protein, Pseudomonas aeruginosa
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0028-4793
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pubmed:author |
pubmed-author:BrylaD ADA,
pubmed-author:DayR NRN,
pubmed-author:HoV AVA,
pubmed-author:KhiemH BHB,
pubmed-author:KossaczkaZZ,
pubmed-author:LinF YFY,
pubmed-author:RobbinsJ BJB,
pubmed-author:SchneersonRR,
pubmed-author:ShiloachJJ,
pubmed-author:SzuS CSC,
pubmed-author:ThanhT CTC,
pubmed-author:TrachD DDD
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pubmed:issnType |
Print
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pubmed:day |
26
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pubmed:volume |
344
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1263-9
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:11320385-ADP Ribose Transferases,
pubmed-meshheading:11320385-Antibodies, Bacterial,
pubmed-meshheading:11320385-Bacterial Toxins,
pubmed-meshheading:11320385-Child, Preschool,
pubmed-meshheading:11320385-Double-Blind Method,
pubmed-meshheading:11320385-Exotoxins,
pubmed-meshheading:11320385-Female,
pubmed-meshheading:11320385-Humans,
pubmed-meshheading:11320385-Immunoglobulin G,
pubmed-meshheading:11320385-Male,
pubmed-meshheading:11320385-Polysaccharides, Bacterial,
pubmed-meshheading:11320385-Salmonella typhi,
pubmed-meshheading:11320385-Treatment Outcome,
pubmed-meshheading:11320385-Typhoid Fever,
pubmed-meshheading:11320385-Typhoid-Paratyphoid Vaccines,
pubmed-meshheading:11320385-Vaccines, Conjugate,
pubmed-meshheading:11320385-Virulence Factors
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pubmed:year |
2001
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pubmed:articleTitle |
The efficacy of a Salmonella typhi Vi conjugate vaccine in two-to-five-year-old children.
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pubmed:affiliation |
National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892-7510, USA. link@exchange.nih.gov
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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