Linked Life Data

11319060

Source:http://linkedlifedata.com/resource/pubmed/id/11319060

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2001-4-25
pubmed:abstractText
The primary pathophysiologic abnormality in achalasia is loss of intrinsic inhibitory innervation of the lower esophageal sphincter and smooth muscle segment of the esophageal body. Disease of the extrinsic (vagal) nervous system and esophageal musculature may also be present, but these are less consistent findings and could represent secondary phenomena. Inflammation within the esophageal myenteric plexus is pathognomonic of the disease, but the cause of this inflammation is uncertain. Autoimmunity and previous viral infection have been hypothesized, but remain unproven.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1052-5157
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
249-66, vi
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Etiology and pathogenesis of achalasia.
pubmed:affiliation
Gastrointestinal Diseases Research Unit, Queen's University, Kingston, Ontario, Canada. patersow@hdh.kari.net
pubmed:publicationType
Journal Article, Review