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rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5
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pubmed:dateCreated |
2001-4-25
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|
pubmed:abstractText |
The renal K(+) channel ROMK (Kir1.1) controls salt reabsorption in the kidney. Loss-of-function mutations in this channel cause hyperprostaglandin E syndrome/antenatal Bartter syndrome (HPS/aBS), which is characterized by severe renal salt and fluid wasting.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
May
|
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pubmed:issn |
0085-2538
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
59
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1803-11
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:11318951-Animals,
pubmed-meshheading:11318951-Bartter Syndrome,
pubmed-meshheading:11318951-Base Sequence,
pubmed-meshheading:11318951-Child, Preschool,
pubmed-meshheading:11318951-Codon, Nonsense,
pubmed-meshheading:11318951-DNA Primers,
pubmed-meshheading:11318951-Exons,
pubmed-meshheading:11318951-Female,
pubmed-meshheading:11318951-Genetic Linkage,
pubmed-meshheading:11318951-Humans,
pubmed-meshheading:11318951-Infant,
pubmed-meshheading:11318951-Male,
pubmed-meshheading:11318951-Mutation,
pubmed-meshheading:11318951-Mutation, Missense,
pubmed-meshheading:11318951-Oocytes,
pubmed-meshheading:11318951-Pedigree,
pubmed-meshheading:11318951-Potassium Channels,
pubmed-meshheading:11318951-Potassium Channels, Inwardly Rectifying,
pubmed-meshheading:11318951-Prostaglandins E,
pubmed-meshheading:11318951-Sequence Deletion,
pubmed-meshheading:11318951-Syndrome,
pubmed-meshheading:11318951-Transfection,
pubmed-meshheading:11318951-Xenopus
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pubmed:year |
2001
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pubmed:articleTitle |
Functional heterogeneity of ROMK mutations linked to hyperprostaglandin E syndrome.
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pubmed:affiliation |
Department of Pediatrics, Philipps-University, Marburg, Germany.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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