Source:http://linkedlifedata.com/resource/pubmed/id/11318368
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
2001-4-24
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pubmed:abstractText |
Between May 1996 and February 1997, 27 horses and a veterinary student at a veterinary teaching hospital developed apparent nosocomial Salmonella Typhimurium infection. The source of the multiple-drug resistant Salmonella Typhimurium was a neonatal foal admitted for treatment of septicemia. A high infection rate (approx 13% of hospitalized horses) coupled with a high case fatality rate (44%) for the initial 18 horses affected led to a decision to close the hospital for extensive cleaning and disinfection. Despite this effort and modification of hospital policies for infection control, 9 additional horses developed nosocomial Salmonella Typhimurium infection during the 6 months after the hospital reopened. Polymerase chain reaction testing of environmental samples was useful in identifying a potential reservoir of the organism in drains in the isolation facility. Coupled with clinical data, comparison of antimicrobial resistance patterns of Salmonella Typhimurium isolates provided a rapid initial means to support or refute nosocomial infection. Although minor changes in the genome of these isolates developed over the course of the outbreak, pulsed-field gel electrophoresis testing further supported that salmonellosis was nosocomial in all 27 horses.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0003-1488
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
218
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1152-9, 1100
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:11318368-Animals,
pubmed-meshheading:11318368-Cross Infection,
pubmed-meshheading:11318368-Disease Outbreaks,
pubmed-meshheading:11318368-Drug Resistance, Microbial,
pubmed-meshheading:11318368-Electrophoresis, Gel, Pulsed-Field,
pubmed-meshheading:11318368-Feces,
pubmed-meshheading:11318368-Female,
pubmed-meshheading:11318368-Horse Diseases,
pubmed-meshheading:11318368-Horses,
pubmed-meshheading:11318368-Hospitals, Animal,
pubmed-meshheading:11318368-Hospitals, Teaching,
pubmed-meshheading:11318368-Male,
pubmed-meshheading:11318368-Michigan,
pubmed-meshheading:11318368-Polymerase Chain Reaction,
pubmed-meshheading:11318368-Salmonella,
pubmed-meshheading:11318368-Salmonella Infections, Animal,
pubmed-meshheading:11318368-Serotyping
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pubmed:year |
2001
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pubmed:articleTitle |
An outbreak of salmonellosis among horses at a veterinary teaching hospital.
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pubmed:affiliation |
Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing 48824-1314, USA.
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pubmed:publicationType |
Journal Article
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