Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2001-4-24
pubmed:abstractText
Ninety-two children 5 to 14 years of age living in areas exposed to the radioactive fallout from Chernobyl with recurrent respiratory infections (RRIs) were treated after randomization with either Viscum album praeparatum mali or pini (Iscador M or P). The dosage was two subcutaneous injections a week for 5 weeks with individual doses of 0.001 mg to 1.0 mg. Both Viscum album preparations were effective in significantly reducing clinical symptoms. One year after a single treatment course, the frequency of RRI relapses decreased by 78% and 73%, respectively. Immunomodulatory effects were assessed by investigation of lymphocyte subsets, natural killer (NK) cell activity, phagocytic and oxidative activity of polymorphonuclear leukocytes, and antiviral activity of serum before and 1 week after treatment. Viscum album therapy resulted in normalization of initial immune indices either below or above the normal ranges. High levels of antiviral activity before treatment were significantly decreased by Viscum album mali. Viscum album treatment should be studied further in children with RRI.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1075-2765
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
195-203
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed-meshheading:11317168-Adolescent, pubmed-meshheading:11317168-Adult, pubmed-meshheading:11317168-Antineoplastic Agents, Phytogenic, pubmed-meshheading:11317168-Child, pubmed-meshheading:11317168-Female, pubmed-meshheading:11317168-Humans, pubmed-meshheading:11317168-Immunity, Cellular, pubmed-meshheading:11317168-Immunocompromised Host, pubmed-meshheading:11317168-Injections, Subcutaneous, pubmed-meshheading:11317168-Male, pubmed-meshheading:11317168-Mistletoe, pubmed-meshheading:11317168-Plant Extracts, pubmed-meshheading:11317168-Plant Proteins, pubmed-meshheading:11317168-Plants, Medicinal, pubmed-meshheading:11317168-Power Plants, pubmed-meshheading:11317168-Radioactive Fallout, pubmed-meshheading:11317168-Radioactive Hazard Release, pubmed-meshheading:11317168-Recurrence, pubmed-meshheading:11317168-Respiratory Tract Infections, pubmed-meshheading:11317168-Ukraine
pubmed:year
2000
pubmed:articleTitle
Immunomodulatory and clinical effects of Viscum album (Iscador M and Iscador P) in children with recurrent respiratory infections as a result of the Chernobyl nuclear accident.
pubmed:affiliation
Institute of Pediatrics, Obstetrics and Gynecology, Academy of Medical Sciences, Kiev 1st Clinical Center, Arlesheim, Switzerland.
pubmed:publicationType
Journal Article, Clinical Trial, Randomized Controlled Trial