Source:http://linkedlifedata.com/resource/pubmed/id/11316159
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2001-4-23
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pubmed:abstractText |
Recent studies have suggested that a susceptibility gene located on chromosome 16 and designated IBD1 may contribute to the development of Crohn's disease (CD). However, these findings were observed in predominantly non-Jewish populations; in the three studies where Ashkenazi Jews were included for analysis, the results have been widely divergent. Because Ashkenazi Jews are known to have a higher incidence of the disease than non-Jews, we sought to determine whether this previously reported linkage could be extended to the Ashkenazi population. In addition, we examined whether Ashkenazi Jewish patients with an early age of onset (< or = 21 yr) showed greater evidence of linkage to this locus.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0002-9270
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
96
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1127-32
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:11316159-Adult,
pubmed-meshheading:11316159-Age Factors,
pubmed-meshheading:11316159-Chromosomes, Human, Pair 16,
pubmed-meshheading:11316159-Crohn Disease,
pubmed-meshheading:11316159-Female,
pubmed-meshheading:11316159-Genetic Linkage,
pubmed-meshheading:11316159-Genetic Predisposition to Disease,
pubmed-meshheading:11316159-Humans,
pubmed-meshheading:11316159-Jews,
pubmed-meshheading:11316159-Male
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pubmed:year |
2001
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pubmed:articleTitle |
The IBD1 locus for susceptibility to Crohn's disease has a greater impact in Ashkenazi Jews with early onset disease.
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pubmed:affiliation |
Department of Medicine, North Shore University Hospital/New York University School of Medicine, Manhasset 11030, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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