Linked Life Data

11303113

Source:http://linkedlifedata.com/resource/pubmed/id/11303113

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2001-4-16
pubmed:abstractText
The flexibility of the human motor system is remarkable. Even when parts of the system are damaged, the output often remains optimal or near optimal. The neuromotor system is designed to keep the output optimal by shifting between input sources. This capability is termed the principle of continuous adaptation. This article describes an experiment in which patients suffering from a hereditary motor and sensory neuropathy, type 1a (Charcot Marie Tooth disease, type 1a), had to perform fine motor movements. We examined whether they were able to regulate these movements in spite of the fact that the somatosensory input and motor output was substantially impaired as a result of the chronic, slowly progressing neuropathy. It was predicted that these patients were able to perform fine movements as long as the movements were well known and over-learned. Furthermore, it was predicted that these patients would compensate for the loss of somatosensory information by becoming more dependent on vision. A second prediction was that the quality of the motor performance would break down when these patients had to perform a novel motor pattern. The performance of the patients (n=10) was contrasted with the performance of 20 healthy subjects. The results indicated that the patients, indeed, were able to perform the over-learned movements and that their performance deteriorated significantly when they had to perform a novel motor pattern. No indication, however, could be found for visual compensation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1087-1640
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
200-14
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
The regulation of fine movements in patients with Charcot Marie Tooth, type Ia: some ideas about continuous adaptation.
pubmed:affiliation
Institute of Human Movement Sciences, University of Groningen, P. O. Box 196, 9700 AD Groningen, The Netherlands.
pubmed:publicationType
Journal Article