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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
14
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pubmed:dateCreated |
2001-4-11
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pubmed:abstractText |
alpha(v)beta(3)-Integrin receptors are upregulated in atherosclerotic arteries and play a key role in smooth muscle cell and possibly inflammatory cell migration. We hypothesized that after balloon angioplasty (BA) of atherosclerotic arteries, selective inhibition of the alpha(v)beta(3)-receptor by XT199, a small-molecule, non-peptide-selective alpha(v)beta(3)-receptor antagonist, would reduce restenosis.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1524-4539
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
10
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pubmed:volume |
103
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1906-11
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:11294811-Actins,
pubmed-meshheading:11294811-Angioplasty, Balloon,
pubmed-meshheading:11294811-Animals,
pubmed-meshheading:11294811-Arterial Occlusive Diseases,
pubmed-meshheading:11294811-Arteriosclerosis,
pubmed-meshheading:11294811-Cell Adhesion,
pubmed-meshheading:11294811-Cells, Cultured,
pubmed-meshheading:11294811-Chemokine CCL2,
pubmed-meshheading:11294811-Cholesterol,
pubmed-meshheading:11294811-Dose-Response Relationship, Drug,
pubmed-meshheading:11294811-Femoral Artery,
pubmed-meshheading:11294811-Imidazoles,
pubmed-meshheading:11294811-Immunohistochemistry,
pubmed-meshheading:11294811-Intercellular Adhesion Molecule-1,
pubmed-meshheading:11294811-Macrophages,
pubmed-meshheading:11294811-Male,
pubmed-meshheading:11294811-Muscle, Smooth, Vascular,
pubmed-meshheading:11294811-Rabbits,
pubmed-meshheading:11294811-Receptors, Vitronectin,
pubmed-meshheading:11294811-Recurrence,
pubmed-meshheading:11294811-Time Factors,
pubmed-meshheading:11294811-Tunica Intima,
pubmed-meshheading:11294811-Tunica Media,
pubmed-meshheading:11294811-Vascular Cell Adhesion Molecule-1
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pubmed:year |
2001
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pubmed:articleTitle |
Selective alpha(v)beta(3)-receptor blockade reduces macrophage infiltration and restenosis after balloon angioplasty in the atherosclerotic rabbit.
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pubmed:affiliation |
University of Virginia, Charlottesville, VA, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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