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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
14
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pubmed:dateCreated |
2001-4-11
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pubmed:abstractText |
Extracellular superoxide dismutase (Ec-SOD) may protect the heart against myocardial infarction (MI) because of its extended half-life and capacity to bind heparan sulfate proteoglycans on cellular surfaces. Accordingly, we used direct gene transfer to increase systemic levels of Ec-SOD and determined whether this gene therapy could protect against MI.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1524-4539
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
10
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pubmed:volume |
103
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1893-8
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:11294809-Animals,
pubmed-meshheading:11294809-Arrhythmias, Cardiac,
pubmed-meshheading:11294809-Blood Pressure,
pubmed-meshheading:11294809-COS Cells,
pubmed-meshheading:11294809-Consciousness,
pubmed-meshheading:11294809-Free Radical Scavengers,
pubmed-meshheading:11294809-Gene Expression,
pubmed-meshheading:11294809-Gene Therapy,
pubmed-meshheading:11294809-Heart Rate,
pubmed-meshheading:11294809-Heart Ventricles,
pubmed-meshheading:11294809-Humans,
pubmed-meshheading:11294809-Male,
pubmed-meshheading:11294809-Myocardial Infarction,
pubmed-meshheading:11294809-Myocardial Reperfusion Injury,
pubmed-meshheading:11294809-Organ Size,
pubmed-meshheading:11294809-RNA, Messenger,
pubmed-meshheading:11294809-Rabbits,
pubmed-meshheading:11294809-Recombinant Fusion Proteins,
pubmed-meshheading:11294809-Superoxide Dismutase
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pubmed:year |
2001
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pubmed:articleTitle |
Gene therapy with extracellular superoxide dismutase protects conscious rabbits against myocardial infarction.
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pubmed:affiliation |
Cardiology Research Laboratory, Division of Cardiology, University of Louisville and Jewish Hospital Heart and Lung Institute, Louisville, KY, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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