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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2001-4-9
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pubmed:abstractText |
Passive immunization with monoclonal antibodies (MAbs) to melanin prolonged the survival of and reduced the fungal burden in Cryptococcus neoformans-infected mice in comparison to controls. MAbs to melanin reduced the growth rate of in vitro-melanized C. neoformans cells, suggesting a new mechanism of antibody-mediated protection.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0019-9567
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
69
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3410-2
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:11292764-Animals,
pubmed-meshheading:11292764-Antibodies, Monoclonal,
pubmed-meshheading:11292764-Cryptococcosis,
pubmed-meshheading:11292764-Cryptococcus neoformans,
pubmed-meshheading:11292764-Female,
pubmed-meshheading:11292764-Immunization, Passive,
pubmed-meshheading:11292764-Levodopa,
pubmed-meshheading:11292764-Melanins,
pubmed-meshheading:11292764-Mice,
pubmed-meshheading:11292764-Mice, Inbred C57BL
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pubmed:year |
2001
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|
pubmed:articleTitle |
Passive immunization with melanin-binding monoclonal antibodies prolongs survival of mice with lethal Cryptococcus neoformans infection.
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pubmed:affiliation |
Department of Microbiology & Immunology, Albert Einstein College of Medicine, Bronx, New York 10461, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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