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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2001-4-9
pubmed:abstractText
Postictal EEG suppression and slowing recorded with scalp electrodes in patients with partial epilepsy is often maximal over the cortical area of ictal onset. The aim of this study was to determine whether a quantitative relationship exists between immediate postictal EEG suppression and hippocampal atrophy. Immediate postictal EEG was analyzed in 31 scalp-recorded seizures obtained from 8 patients who underwent temporal lobectomy with seizure-free outcomes (2 left, 6 right). Quantitative EEG analysis was performed using a temporal power asymmetry index for each frequency band. The hippocampal asymmetry (left-to-right ratio) based on T1- and T2-weighted MR images was determined by hippocampal volumetric analysis. The relationship between the average temporal power asymmetry index and either T1 or T2 hippocampal asymmetry ratio was assessed for each frequency band using Pearson's correlation coefficient. Only correlations of the temporal power asymmetry index with T1 hippocampal asymmetry were significant for the total bands (r = 0.768, P < 0.026) and 8-bands (r = 0.728, P < 0.041). The findings suggest that a quantitative relationship exists between postictal EEG suppression in the 6-frequency band and hippocampal atrophy in temporal lobe epilepsy.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0736-0258
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2-8
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Postictal EEG suppression and hippocampal atrophy in temporal lobe epilepsy.
pubmed:affiliation
Louisiana State University Comprehensive Epilepsy Center, New Orleans, USA.
pubmed:publicationType
Journal Article