Linked Life Data

11286502

Source:http://linkedlifedata.com/resource/pubmed/id/11286502

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2001-4-5
pubmed:abstractText
Corticotropin-releasing hormone (CRH) is a 41 amino acid polypeptide that exerts a wide spectrum of hypothalamic and extrahypothalamic functions. Moreover, the placenta and other intrauterine tissues produce and secrete immunoreactive CRH. It has been demonstrated that placental CRH is secreted into the maternal circulation in large amounts during the third trimester of human pregnancy and may play an important role in the onset of labor. CRH exerts a number of functions within the intratuterine environment like induction of prostaglandin production and maintenance of the placental blood flow. Here we present an overview of current knowledge about the CRH receptor subtypes and their signaling properties within the feto-placental unit.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1096-7192
pubmed:author
pubmed:copyrightInfo
Copyright 2001 Academic Press.
pubmed:issnType
Print
pubmed:volume
72
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
287-96
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
The role of corticotropin-releasing hormone receptors in placenta and fetal membranes during human pregnancy.
pubmed:affiliation
The Sir Quinton Hazel Research Centre for Molecular Medicine, University of Warwick, Coventry, CV4 7AL, United Kingdom.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't