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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2001-4-3
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pubmed:abstractText |
The cellular basis of the cardioprotective effects of estrogen are largely unknown. An inhibitory effect on vascular smooth muscle (VSM) growth has been proposed. We examined the effect of 17beta-estradiol (E2) on mechanical strain-induced mitogenesis in human fetal VSM cells. METHODS and
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0008-6363
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
108-14
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11282083-Cell Culture Techniques,
pubmed-meshheading:11282083-Cell Division,
pubmed-meshheading:11282083-DNA,
pubmed-meshheading:11282083-Down-Regulation,
pubmed-meshheading:11282083-Estradiol,
pubmed-meshheading:11282083-Female,
pubmed-meshheading:11282083-Humans,
pubmed-meshheading:11282083-Mitosis,
pubmed-meshheading:11282083-Muscle, Smooth, Vascular,
pubmed-meshheading:11282083-Platelet-Derived Growth Factor,
pubmed-meshheading:11282083-RNA, Messenger,
pubmed-meshheading:11282083-Receptors, Estrogen,
pubmed-meshheading:11282083-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:11282083-Sp1 Transcription Factor,
pubmed-meshheading:11282083-Stress, Mechanical
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pubmed:year |
2001
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pubmed:articleTitle |
Estrogen inhibits mechanical strain-induced mitogenesis in human vascular smooth muscle cells via down-regulation of Sp-1.
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pubmed:affiliation |
Hormones and The Vasculature Laboratory, Baker Institute and Alfred Heart Centre, Alfred Hospital, Melbourne, Australia.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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