Source:http://linkedlifedata.com/resource/pubmed/id/11277589
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rdf:type | |
lifeskim:mentions |
umls-concept:C0007450,
umls-concept:C0013819,
umls-concept:C0027882,
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umls-concept:C0439849,
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umls-concept:C0445223,
umls-concept:C0871261,
umls-concept:C0949370,
umls-concept:C1442792,
umls-concept:C1552599,
umls-concept:C1704632,
umls-concept:C1704787,
umls-concept:C1706817,
umls-concept:C1709059,
umls-concept:C2911692
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pubmed:issue |
4
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pubmed:dateCreated |
2001-3-29
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pubmed:abstractText |
Spike activity of single perigeniculate (PGN) neurons was recorded in the anaesthetized (N2O/halothane) and paralysed cat during presentation of moving gratings of optimal spatial frequency. Typically, the ongoing (tonic, spontaneous) activity of PGN cells increased during a rise in EEG delta power accompanied by a reduction and often a total loss of spike rate modulation by the moving grating. The opposite behaviour was found when the EEG delta power vanished. Micro-iontophoretically applied acetylcholine (ACh) had an effect similar to a decrease in EEG delta power, decreasing ongoing activity but increasing the response modulation depth. The opposite effect could be achieved with the excitatory action of serotonin (5-HT), mimicking a strengthened EEG delta power. These data support previous data indicating that PGN neurons contribute to spatio-temporal tuning of subcortical visual activity in a state-dependent way.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0959-4965
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
26
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
815-20
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11277589-Acetylcholine,
pubmed-meshheading:11277589-Anesthesia,
pubmed-meshheading:11277589-Animals,
pubmed-meshheading:11277589-Cats,
pubmed-meshheading:11277589-Electroencephalography,
pubmed-meshheading:11277589-Female,
pubmed-meshheading:11277589-Geniculate Ganglion,
pubmed-meshheading:11277589-Male,
pubmed-meshheading:11277589-Photic Stimulation,
pubmed-meshheading:11277589-Serotonin,
pubmed-meshheading:11277589-Visual Pathways
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pubmed:year |
2001
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pubmed:articleTitle |
Changes in response modulation of cat perigeniculate neurons related to EEG state and application of neuromodulators.
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pubmed:affiliation |
Department of Neurophysiology, Medical Faculty, Ruhr-University Bochum, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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