|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2001-3-29
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|
pubmed:abstractText |
A novel synthetic strategy is described which may be used to prepare analogues of the antimalarial, fungal metabolite apicidin. Compared to the natural product, one analogue shows potent and selective activity in vitro against the parasite Trypanosoma brucei and low mammalian cell toxicity.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
0960-894X
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|
pubmed:author |
pubmed-author:BertaJJ,
pubmed-author:CleggWW,
pubmed-author:CroftS LSL,
pubmed-author:ElsegoodM RMR,
pubmed-author:HolmesA BAB,
pubmed-author:Jaxa-ChamiecAA,
pubmed-author:KeaveyK NKN,
pubmed-author:KranzMM,
pubmed-author:MCGILLC MCM,
pubmed-author:MurrayP JPJ,
pubmed-author:SealeP WPW,
pubmed-author:SteadPP,
pubmed-author:TaylorSS,
pubmed-author:UptonR JRJ
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|
pubmed:issnType |
Print
|
|
pubmed:day |
26
|
|
pubmed:volume |
11
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
773-6
|
|
pubmed:dateRevised |
2006-11-15
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|
pubmed:meshHeading |
|
|
pubmed:year |
2001
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|
pubmed:articleTitle |
The synthesis of cyclic tetrapeptoid analogues of the antiprotozoal natural product apicidin.
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|
pubmed:affiliation |
Glaxo Wellcome Cambridge Chemistry Laboratory, UK.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
