Source:http://linkedlifedata.com/resource/pubmed/id/11277423
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2001-3-29
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pubmed:abstractText |
A 58-year-old patient had been treated for recurrent gastritis. Numerous gastroscopies indicated hemorrhagic gastritis combined with increasingly severe anemia. The patient was admitted with a hemoglobin of 4.4 g/dL. Gastroscopy showed marked antral angiodysplasia. Serum samples for gastrin were taken and found to be elevated (170-250 U/mL). The search for a gastrin-producing tumor with abdominal ultrasound, computed tomography, octreotide scan, and secretin test was negative, but angiography detected a pancreas tumor with a 2-cm diameter. Partial pancreatectomy and partial gastrectomy were performed. Immunohistochemical examination of the tumor did not show a gastrinoma but did show glucagon-reactive tissue. Further tumors or elevated plasma hormone levels were not detected, and a multiple endocrine neoplasia type I syndrome could be excluded. We thus found antral angiodysplasia with hypergastrinemia leading to detection of a glucagonoma diagnosed by immunohistochemistry. After more than 4 years of follow-up, the patient is without any symptoms or signs of relapse or secondary hormone syndrome.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1541-2016
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
92-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11277423-Diagnosis, Differential,
pubmed-meshheading:11277423-Gastric Antral Vascular Ectasia,
pubmed-meshheading:11277423-Gastrins,
pubmed-meshheading:11277423-Glucagon,
pubmed-meshheading:11277423-Glucagonoma,
pubmed-meshheading:11277423-Humans,
pubmed-meshheading:11277423-Immunohistochemistry,
pubmed-meshheading:11277423-Male,
pubmed-meshheading:11277423-Middle Aged,
pubmed-meshheading:11277423-Multiple Endocrine Neoplasia Type 1,
pubmed-meshheading:11277423-Pancreatic Neoplasms,
pubmed-meshheading:11277423-Pyloric Antrum
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pubmed:year |
2001
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pubmed:articleTitle |
Immunohistochemical assessment of an asymptomatic glucagonoma in a patient with hypergastrinemia and marked antral angiodysplasia.
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pubmed:affiliation |
Department of Medicine I, Institute of Pathology, Landeskliniken Salzburg, Austria, EU.
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
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