Source:http://linkedlifedata.com/resource/pubmed/id/11271265
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2001-2-22
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pubmed:abstractText |
Obliterative bronchiolitis (OB) continues to be a major cause of morbidity and mortality following heart-lung transplantation. We compared the incidence of death from obliterative bronchiolitis in 19 children and 72 adults following heart-lung transplantation at our institutes. The incidence of death from OB at 2 years was 38% for children compared with 17% for adults, this difference was significant (Cox-Mantel Z value = 2.243, P < 0.05). The frequency of acute lung rejection and persistent lung rejection, previously described as risk factors for OB in adults, were significantly more common in children, P = 0.004 and P = 0.001, respectively. Average forced expiratory volume in 1 s was lower in children than in adults for each 3-month period after transplantation (P < 0.001). In conclusion, identified risk factors for the development of OB were more common, and the risk of death from OB was greater in children than in adults following heart-lung transplantation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0934-0874
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
7 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
S404-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11271265-Adolescent,
pubmed-meshheading:11271265-Adult,
pubmed-meshheading:11271265-Age Factors,
pubmed-meshheading:11271265-Bronchiolitis Obliterans,
pubmed-meshheading:11271265-Child,
pubmed-meshheading:11271265-Child, Preschool,
pubmed-meshheading:11271265-Graft Rejection,
pubmed-meshheading:11271265-Heart-Lung Transplantation,
pubmed-meshheading:11271265-Humans,
pubmed-meshheading:11271265-Middle Aged,
pubmed-meshheading:11271265-Postoperative Complications
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pubmed:year |
1994
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pubmed:articleTitle |
Paediatric incidence of acute rejection and obliterative bronchiolitis: a comparison with adults.
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pubmed:affiliation |
Division of Thoracic Diseases, Mayo Clinic, Rochester, MN 55905, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study
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