Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1975-8-8
pubmed:abstractText
Previous experiments on compensatory hypertrophy of the splenic parenchyma after partial splenectomy, permitted us to observe lesions of the part of the pancreas in contact with the spleen. This part of the gland is supplied only by the splenic artery and suffers from some degree of ischemia during splenectomy. The object of this research was to seek, as a routine, pancreatic disease after splenectomy. 32 adult rabbits were used. Partial splenectomy carried out in 15 cases, removed about 2/3rds of the spleen and involved ligature of 4 or 5 splenic and mesenteric arterio-venous pedicles. Total splenectomy, carried out in 17 cases, included ligature of the splenic arteriovenous trunk and 3 or 4 spleno-gastric and spleno-mesenteric arterio-venous pedicles. These operations were followed by more or less intense stasis extending to the splenic part of the pancreas. The animals were examined one week and 8 months afterwards. All the rabbits, except one, had pancreatic lesions. The most severe and extensive lesions, including large areas of cytosteato-necrosis with, in 11 cases, pseudo-cysts, with caseation, followed total splenectomy. Partial splenectomy gave rise to 6 pseudocysts including 2 containing blood and 9 cases with milder lesions including involution, rarefaction and sometimes disappearance of the gland which had suffered from ischemia. In these splenectomies, ligature of the splenic arterio-venous pedicles supplying the pancreas were responsible for pancreatic disease.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0021-7697
pubmed:author
pubmed:issnType
Print
pubmed:volume
109
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
119-26
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
[Segmental pancreatic lesions after partial or total splenectomy in rabbits].
pubmed:publicationType
Journal Article, English Abstract