Source:http://linkedlifedata.com/resource/pubmed/id/11264027
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
2001-3-26
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pubmed:abstractText |
Neisseria meningitidis is an important cause of serious bacterial infections in children. We undertook a study to identify meningococcal infections of the blood, cerebrospinal fluid, or both of children in a defined geographic area to describe the burden of disease and the spectrum of illness. We reviewed the medical records of all children aged <18 years who had meningococcal infections at the 4 pediatric referral hospitals in Boston, Massachusetts, from 1981 through 1996. We identified 231 patients with meningococcal disease; of these 231 patients, 194 (84%) had overt disease and 37 (16%) had unsuspected disease. Clinical manifestations included meningitis in 150 patients, hypotension in 26, and purpura in 17. Sixteen patients (7%) died. Although meningococcal disease is devastating to a small number of children, we found that the burden of pediatric disease that it caused at the 4 pediatric referral centers in this geographic region was limited; that patients with overt meningococcal disease are most likely to have meningitis; and that individual practitioners are unlikely to encounter a patient with unsuspected meningococcal disease.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1058-4838
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
32
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1004-9
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:11264027-Adolescent,
pubmed-meshheading:11264027-Boston,
pubmed-meshheading:11264027-Child,
pubmed-meshheading:11264027-Child, Preschool,
pubmed-meshheading:11264027-Female,
pubmed-meshheading:11264027-Humans,
pubmed-meshheading:11264027-Male,
pubmed-meshheading:11264027-Meningococcal Infections,
pubmed-meshheading:11264027-Neisseria meningitidis,
pubmed-meshheading:11264027-Prospective Studies
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pubmed:year |
2001
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pubmed:articleTitle |
Meningococcal disease among children who live in a large metropolitan area, 1981-1996.
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pubmed:affiliation |
Emergency Medicine, Department of Medicine, Children's Hospital Boston, USA. wang@chla.usc.edu
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pubmed:publicationType |
Journal Article
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