Source:http://linkedlifedata.com/resource/pubmed/id/11262057
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
2001-3-23
|
pubmed:abstractText |
This study aimed at evaluating the antioxidative activity of crude hsian-tsao leaf gum extracted by sodium bicarbonate solutions and precipitated by 70% ethanol. The antioxidative activities, including the radical-scavenging effects, Fe(2+)-chelating ability, and reducing power as well as the inhibition of FeSO(4)-H(2)O(2)-induced malondialdehyde formation in rat tissue homogenate were studied in vitro. It was found that the antioxidative effect provided by hsian-tsao leaf gum was strongly concentration dependent. In general, the antioxidative activity increased with increasing gum concentration, to a certain extent, and then leveled off with further increase in gum concentration. A concentrtaion-dependent kinetics for the rate of change in antioxidative activity was proposed. The antioxidative activity constant (k) and the half-inhibition concentration (IC(50)) for each antioxidative reaction studied were calculated. From a comparison of the IC(50) values for different antioxidative reactions, it seemed that hsian-tsao leaf gum was more effective in scavenging superoxide radicals than chelating Fe(2+) or scavenging alpha,alpha-diphenyl-beta-picrylhydrazyl (DPPH) radicals. As compared to the commercial antioxidants, hsian-tsao leaf gum showed less scavenging effect on the DPPH radical and reducing power but better superoxide radical-scavenging effect and Fe(2+)-chelating ability than alpha-tocopherol and BHT.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antioxidants,
http://linkedlifedata.com/resource/pubmed/chemical/Ethanol,
http://linkedlifedata.com/resource/pubmed/chemical/Free Radical Scavengers,
http://linkedlifedata.com/resource/pubmed/chemical/Iron,
http://linkedlifedata.com/resource/pubmed/chemical/Malondialdehyde,
http://linkedlifedata.com/resource/pubmed/chemical/Plant Extracts,
http://linkedlifedata.com/resource/pubmed/chemical/Sodium Bicarbonate,
http://linkedlifedata.com/resource/pubmed/chemical/Superoxides
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0021-8561
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
49
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
963-8
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:11262057-Animals,
pubmed-meshheading:11262057-Antioxidants,
pubmed-meshheading:11262057-Asteraceae,
pubmed-meshheading:11262057-Ethanol,
pubmed-meshheading:11262057-Free Radical Scavengers,
pubmed-meshheading:11262057-Iron,
pubmed-meshheading:11262057-Lipid Peroxidation,
pubmed-meshheading:11262057-Liver,
pubmed-meshheading:11262057-Malondialdehyde,
pubmed-meshheading:11262057-Plant Extracts,
pubmed-meshheading:11262057-Plant Leaves,
pubmed-meshheading:11262057-Rats,
pubmed-meshheading:11262057-Rats, Sprague-Dawley,
pubmed-meshheading:11262057-Sodium Bicarbonate,
pubmed-meshheading:11262057-Superoxides
|
pubmed:year |
2001
|
pubmed:articleTitle |
Studies on the antioxidative activities of Hsian-tsao (Mesona procumbens Hemsl) leaf gum.
|
pubmed:affiliation |
Department of Food and Nutrition, Providence University, 200 Chungchi Road, Shalu, Taichung 433, Taiwan.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|