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pubmed:abstractText |
Roles of central adrenergic receptors and opioid receptors in the depressor-bradycardia effect of 3V, 2Hz "Tinggong-Quchi" electroacupuncture (the EA-DpB, i.e.the depressor bradycardia induced by electroacupuncture) were studied by intracerebroventricula (icv) injection of prazosin, yohimbine or propanol, naloxone or by intra-arachnoid (ith) injection of naloxone. Voltage-dependent depressor effects were induced by 2Hz "Tinggong-Quchi" acupuncture. The depressor effect of 3V, 2Hz " Tinggong-Quchi " acupuncture was attenuated by icv injection of a beta-receptor antagonist-propranolol, but was not blocked by the icv injection of an alpha1 -or (alpha2 -receptor antagonist prazosin or yohimbine. Icv injected naloxone but not ith injected naloxone blocked or reversed the EA-DpB. Results suggest that central P-receptors or opioid receptors in the brain are selectively involved in the EA-DpB.
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