Source:http://linkedlifedata.com/resource/pubmed/id/11260258
Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
2001-3-22
|
| pubmed:abstractText |
tob is a member of a gene family with anti-proliferative function. Over-expression of Tob in NIH3T3 cells results in the suppression of cell proliferation. The growth suppression is hampered by the presence of activated ErbB2 kinase. The molecular mechanisms by which Tob suppresses cell growth and by which ErbB2 abrogates Tob function remain to be elucidated.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
1356-9597
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
6
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
131-8
|
| pubmed:dateRevised |
2009-11-19
|
| pubmed:meshHeading |
pubmed-meshheading:11260258-3T3 Cells,
pubmed-meshheading:11260258-Animals,
pubmed-meshheading:11260258-Carrier Proteins,
pubmed-meshheading:11260258-Cell Division,
pubmed-meshheading:11260258-Mice,
pubmed-meshheading:11260258-Phosphorylation,
pubmed-meshheading:11260258-Protein Binding,
pubmed-meshheading:11260258-Ribosomal Protein S6 Kinases
|
| pubmed:year |
2001
|
| pubmed:articleTitle |
A serine/threonine kinase p90rsk1 phosphorylates the anti-proliferative protein Tob.
|
| pubmed:affiliation |
Department of Oncology, Institute of Medical Science, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|