Previous reports suggest that propofol (PPF) may have abuse potential in humans. Hence, we hypothesized that PPF could reinforce self-administration behavior in other species. Positive reinforcing effects of PPF could be interpreted as an index of abuse liability.
Department of Pharmacology and Therapeutics, Louisiana State University Medical Center, Shreveport, 1501 Kings Highway, Shreveport, LA 71130-3932, USA.