Source:http://linkedlifedata.com/resource/pubmed/id/11253070
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
2001-3-16
|
| pubmed:abstractText |
The genetic code evolved in two distinct phases. First, the 'canonical' code emerged before the last universal ancestor; subsequently, this code diverged in numerous nuclear and organelle lineages. Here, we examine the distribution and causes of these secondary deviations from the canonical genetic code. The majority of non-standard codes arise from alterations in the tRNA, with most occurring by post-transcriptional modifications, such as base modification or RNA editing, rather than by substitutions within tRNA anticodons.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
1471-0056
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
2
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
49-58
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:11253070-Animals,
pubmed-meshheading:11253070-Evolution, Molecular,
pubmed-meshheading:11253070-Genetic Code,
pubmed-meshheading:11253070-Mutation,
pubmed-meshheading:11253070-Phylogeny,
pubmed-meshheading:11253070-Protein Biosynthesis,
pubmed-meshheading:11253070-RNA, Transfer,
pubmed-meshheading:11253070-RNA Processing, Post-Transcriptional
|
| pubmed:year |
2001
|
| pubmed:articleTitle |
Rewiring the keyboard: evolvability of the genetic code.
|
| pubmed:affiliation |
Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey 08544, USA. rdknight@princeton.edu
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| pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
|