Linked Life Data

11252521

Source:http://linkedlifedata.com/resource/pubmed/id/11252521

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2001-3-16
pubmed:abstractText
The acute phase of schizophrenia is characterized by the presence of positive, negative and affective symptoms. After recovery, patients still may suffer distressing residual symptoms; they also carry a high risk of relapse which may be associated with further deterioration in their condition. Prompt, early and continued treatment with an effective, well-tolerated antipsychotic agent, is therefore crucial. Typical antipsychotics are poorly tolerated, leading to lack of compliance and relapse. They also lack efficacy in controlling negative and affective symptoms. Atypical compounds such as amisulpride or risperidone are better tolerated. In addition, when compared with either haloperidol or risperidone, amisulpride has been shown to be at least as effective in controlling positive symptoms and significantly superior in alleviating negative symptoms. The onset of action of amisulpride appears more rapid than that of haloperidol. Amisulpride therefore fulfils all the requirements of a first-line agent for the treatment of the acute phase of schizophrenia.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0268-1315
pubmed:author
pubmed:issnType
Print
pubmed:volume
15 Suppl 4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S5-9
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Acute phase of schizophrenia: impact of atypical antipsychotics.
pubmed:affiliation
Service De Psychiatrie, Hôpital Ste Marguerite, Marseilles, France. jazorin@ap-hm.fr
pubmed:publicationType
Journal Article