Linked Life Data

11252065

Source:http://linkedlifedata.com/resource/pubmed/id/11252065

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2001-3-19
pubmed:abstractText
This brief review will discuss an exciting new area in exercise science, namely the role of apoptosis or programmed cell death in exercise. Apoptotic cell death differs morphologically and biochemically from necrotic cell death, although both appear to occur after exercise. Accelerated apoptosis has been documented to occur in a variety of disease states, such as AIDS and Alzheimer's disease, as well as in the aging heart. In striking contrast, failure to activate this genetically regulated cell death may result in cancer and certain viral infections. We will discuss factors that may activate apoptosis during and after exercise and the importance of cell turnover after exercise. We will also discuss differences in apoptosis between lymphocyte and skeletal muscle cells. We speculate that exercise-induced apoptosis is a normal regulatory process that serves to remove certain damaged cells without a pronounced inflammatory response, thus ensuring optimal body function.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0195-9131
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
393-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Apoptosis and exercise.
pubmed:affiliation
Biochemistry of Aging Laboratory, Center for Exercise Science, College of Health and Human Performance, University of Florida, Gainesville, FL 32611, USA.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't