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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
1975-7-24
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pubmed:abstractText |
The five possible ortho-iodinated hexestrols, containing from 1-4 iodines per molecule, have been synthesized as potential iodine-containing estrogenic ligands. After chromatographic separation and purification, each derivative has been fully characterized by spectroscopic methods. [3-H]-3-Iodohexestrol, [131-I]- and [125-I]-3-iodohexestrol, and [125-IA1-3,5-diiodohexestrol have also been prepared. Photolysis of 3,5-diiodohexestrol in methanol results in rapid deiodination to 3-iodohexestrol; further reduction to hexestrol is slower. Photolysis of 3-iodohexestrol in benzene gives 3-phenylhexestrol.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0006-2960
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
22
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1736-41
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1125197-Benzoates,
pubmed-meshheading:1125197-Chromatography, Thin Layer,
pubmed-meshheading:1125197-Hexestrol,
pubmed-meshheading:1125197-Iodine,
pubmed-meshheading:1125197-Iodine Radioisotopes,
pubmed-meshheading:1125197-Magnetic Resonance Spectroscopy,
pubmed-meshheading:1125197-Mass Spectrometry,
pubmed-meshheading:1125197-Molecular Conformation,
pubmed-meshheading:1125197-Photochemistry,
pubmed-meshheading:1125197-Spectrophotometry, Ultraviolet,
pubmed-meshheading:1125197-Structure-Activity Relationship
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pubmed:year |
1975
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pubmed:articleTitle |
Iodohexestrols. I. Synthesis and photoreactivity of iodinated hexestrol derivatives.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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