Source:http://linkedlifedata.com/resource/pubmed/id/11251565
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2001-3-19
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pubmed:abstractText |
Chlorazepate is a benzodiazepine often used for pre-operative anxiolysis. The central metabolite responsible for the pharmacological and probably for the adverse effects of most benzodiazepines, including chlorazepate, is N-desmethyldiazepam. We report a woman who developed a generalized exanthem 1 day after receiving chlorazepate and four other drugs related to anaesthesia for surgery of the larynx. Patch tests pointed to chlorazepate as the culprit drug for the skin rash.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0007-0963
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
144
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
316-20
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11251565-Adult,
pubmed-meshheading:11251565-Clorazepate Dipotassium,
pubmed-meshheading:11251565-Cytokines,
pubmed-meshheading:11251565-Drug Eruptions,
pubmed-meshheading:11251565-Female,
pubmed-meshheading:11251565-Humans,
pubmed-meshheading:11251565-Immunoglobulin E,
pubmed-meshheading:11251565-Interleukin-5,
pubmed-meshheading:11251565-Lymphocyte Activation,
pubmed-meshheading:11251565-Microsomes, Liver,
pubmed-meshheading:11251565-Skin Tests
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pubmed:year |
2001
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pubmed:articleTitle |
In vitro drug allergy detection system incorporating human liver microsomes in chlorazepate-induced skin rash: drug-specific proliferation associated with interleukin-5 secretion.
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pubmed:affiliation |
Department of Dermatology and Allergology, University Hospitals, Rheinisch-Westfälische Technische Hochschule Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany. Bernhardt.Sachs@post.rwth-aachen.de
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pubmed:publicationType |
Journal Article,
In Vitro,
Case Reports,
Research Support, Non-U.S. Gov't
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