Linked Life Data

1125117

Source:http://linkedlifedata.com/resource/pubmed/id/1125117

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1975-8-8
pubmed:abstractText
The function of both right and left sides of the heart was studied during spontaneous attacks of angina pectoris at rest in 7 patients showing ST depression (type I) and 4 showing ST elevation (type II) during the attack. In none of the 44 type I attacks and 29 type II attacks which were recorded did circulatory changes; the latter were different in the two groups. Type I attacks showed: a) a brief fall in arterial pressure, accompanied by b) a rise of right atrial and pulmonary wedge pressures and c) a decrease of cardiac output, right and left stroke work, the mean rate of systolic ejection, and indirect left ventricular pre-ejection dP/dt. In the course of the attack a hypertensive phase followed, which was paralleled by an increase of heart rate, cardiac output, left and right stroke work, and mean systolic ejection rate, left dP/dt; right atrial pressure and wedge pressure remained raised. All of the circulatory functions started to revert towards the pre-attack levels coincident with the waning phase of the electrocardiographic alteration, the latter occurring either spontaneously or after nitroglycerin. Type II attacks for the entire duration of the electrocardiographic changes showed: a) a reduction of arterial pressure, cardiac output, right and left stroke work, mean systolic ejection rate, and left dP/dt, b) a rise of right atrial and wedge pressures, and c) quite small changes of heart rate. When the electrocardiogram started to revert to the pre-attack aspect, the cardiac function rapidly improved and, after a supernormal phase, returned to the basal levels in about 2 minutes. It is concluded: 1) that no circulatory factor interfering with the mechanical effort of the heart is responsible for eliciting spontaneous angina: 2) that in type I attacks right and left ventricular impairment occurs which recovers rapidly, possibly through a sympathetic compensation; 3) that in type II attachs dysfunction of both sides of the heart occurs and persists throughout the episode of electrocardiographic alteration; 4) that the dynamic impairment is probably more severe in type I than in type II angina.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/1125117-13523814, http://linkedlifedata.com/resource/pubmed/commentcorrection/1125117-13560686, http://linkedlifedata.com/resource/pubmed/commentcorrection/1125117-13726264, http://linkedlifedata.com/resource/pubmed/commentcorrection/1125117-14262577, http://linkedlifedata.com/resource/pubmed/commentcorrection/1125117-14314484, http://linkedlifedata.com/resource/pubmed/commentcorrection/1125117-14434946, http://linkedlifedata.com/resource/pubmed/commentcorrection/1125117-4537503, http://linkedlifedata.com/resource/pubmed/commentcorrection/1125117-4923846, http://linkedlifedata.com/resource/pubmed/commentcorrection/1125117-4978186, http://linkedlifedata.com/resource/pubmed/commentcorrection/1125117-4980883, http://linkedlifedata.com/resource/pubmed/commentcorrection/1125117-5056844, http://linkedlifedata.com/resource/pubmed/commentcorrection/1125117-5434111, http://linkedlifedata.com/resource/pubmed/commentcorrection/1125117-5640345, http://linkedlifedata.com/resource/pubmed/commentcorrection/1125117-5677956, http://linkedlifedata.com/resource/pubmed/commentcorrection/1125117-5807693, http://linkedlifedata.com/resource/pubmed/commentcorrection/1125117-6026199, http://linkedlifedata.com/resource/pubmed/commentcorrection/1125117-6066333
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0007-0769
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
401-13
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Left and right heart haemodynamics during spontaneous angina pectoris. Comparison between angina with ST segment depression and angina with ST segment elevation.
pubmed:publicationType
Journal Article