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pubmed-article:11250974pubmed:abstractTextLefradafiban is the orally active prodrug of fradafiban, a glycoprotein IIb/IIIa receptor antagonist. The present phase II study aimed to determine the dose of lefradafiban that provides 80% blockade of the glycoprotein IIb/IIIa receptors by fradafiban, and to study the pharmacodynamics and safety of different doses in patients with stable angina undergoing angioplasty.lld:pubmed
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pubmed-article:11250974pubmed:articleTitlePharmacodynamics and safety of lefradafiban, an oral platelet glycoprotein IIb/IIIa receptor antagonist, in patients with stable coronary artery disease undergoing elective angioplasty.lld:pubmed
pubmed-article:11250974pubmed:affiliationThoraxcenter, Erasmus University and University Hospital Rotterdam, Netherlands. makkerhuis@cardialysis.nllld:pubmed
pubmed-article:11250974pubmed:publicationTypeJournal Articlelld:pubmed
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