Linked Life Data

11248855

Source:http://linkedlifedata.com/resource/pubmed/id/11248855

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2001-3-15
pubmed:abstractText
Cultured human and animal cells are increasingly used as the basis for simplified, direct test systems that have the potential to be more controllable and more reproducible than in vivo test systems. However, if a biological test system is simplified to fundamental levels then it is paramount that the essential components of such a reduced systems are closely defined and reproducible. Thus, minimal requirements for quality standards in cell and tissue culture have to be defined. It is the aim of this GCCP initiative to establish principles for standardisation, rationalisation, and international harmonisation of cell and tissue culture laboratory practices. Therefore, in analogy to Good Laboratory Practice (GLP), a Good Cell Culture Practice (GCCP) was initiated at the 3rd World Congress on Alternatives and Animal Use in the Life Sciences, Bologna, 29. August-2. September 1999. This "Bologna Statement on Good Cell Culture Practice" was presented, discussed, and refined in a Workshop, and a final version was approved at the closing ceremony of the Congress by the scientific audience. Based on the Bologna Statement, an ECVAM Task Force on GCCP was initiated, that is chaired by Thomas Hartung and Sandra Ceocke, in which experts in the field should elaborate minimal requirements for quality standards in cell culture. It is the intention of the GCCP Guidelines to encourage consensus among all concerned with the use of in vitro systems, in order to establish and maintain best laboratory practices, to promote effective quality control systems, to facilitate education and training, to support journal editors, and to help any authorities who need to interpret and apply conclusions based on in vitro data.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1868-596X
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
75-8
pubmed:dateRevised
2010-6-22
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
[Good cell culture practice (GCCP)--an initiative for standardization and quality control of in vitro studies. The establishment of an ECVAM Task Force on GCCP].
pubmed:affiliation
Biochemische Pharmakologie, Universität D-Konstanz. Thomas.Hartung@uni-konstanz.de
pubmed:publicationType
Journal Article, English Abstract