Linked Life Data

11248340

Source:http://linkedlifedata.com/resource/pubmed/id/11248340

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2001-3-15
pubmed:abstractText
The cost of electronic equipment can be a critical barrier to including neurophysiology exercises in biology teaching programs. We describe the construction of a simple and inexpensive AC preamplifier with performance comparable to that of commercial products. The amplifier consists of two integrated circuits in five stages: differential input, fixed gain, variable gain (100 or 1000), low-pass filter (5 or 20 kHz), and 50 or 60 Hz notch filter. We compared our amplifier with two commercial units, the A-M Systems Model 1700 and the Grass P15. The quality of extracellular recording from a typical student preparation (spontaneously active crayfish motor nerve) was the same for all three amplifiers, although our amplifier has slightly higher internal noise than the P15 and slightly lower common-mode rejection than the 1700 and P15. In addition, we describe a simple suction electrode for extracellular nerve recording. It is easily constructed from readily available materials and uses a disposable plastic pipette tip, instead of the traditional glass tip, to contact the nerve. This tip is easily replaced if broken or clogged, and can be adapted to different recording conditions by selecting a different tip size or stretching the plastic. Development of this equipment is part of an ongoing project to promote neuroscience education by expanding the neurophysiology options available to laboratory instructors.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0165-0270
pubmed:author
pubmed:issnType
Print
pubmed:day
30
pubmed:volume
106
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
47-55
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Tools for physiology labs: an inexpensive high-performance amplifier and electrode for extracellular recording.
pubmed:affiliation
Department of Neurobiology and Behavior, Cornell University, Mudd Hall, Ithaca, NY 14853, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't