Source:http://linkedlifedata.com/resource/pubmed/id/11248232
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1-2
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| pubmed:dateCreated |
2001-3-15
|
| pubmed:abstractText |
We generated random Tn5 mutations in Synechocystis sp. PCC 6803 in search for genes involved in the signal transduction cascade for the cyanobacterial gliding motility. One of the non-gliding Tn5 mutants, S1-105, had an insertional inactivation in the slr1044 gene encoding a putative methyl-accepting chemotaxis protein. Interposon mutation on the slr1044 (named ctr1) in the bacterium also eliminated gliding motility. In the interposon mutant, the expression of pilA1 was 5-fold decreased compared with that of wild-type and thick pili, that are believed to be the motor for gliding, could not be observed by an electron microscope. Therefore, we suggest that the Ctr1 protein functions as a transducer that regulates the expression of pilA1, and thus is required for the biogenesis of thick pili.
|
| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Mar
|
| pubmed:issn |
0014-5793
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
9
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| pubmed:volume |
492
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| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
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| pubmed:pagination |
33-8
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| pubmed:dateRevised |
2006-11-28
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| pubmed:meshHeading |
pubmed-meshheading:11248232-Amino Acid Sequence,
pubmed-meshheading:11248232-Bacterial Proteins,
pubmed-meshheading:11248232-Chemotaxis,
pubmed-meshheading:11248232-Cyanobacteria,
pubmed-meshheading:11248232-DNA Transposable Elements,
pubmed-meshheading:11248232-DNA-Binding Proteins,
pubmed-meshheading:11248232-Escherichia coli,
pubmed-meshheading:11248232-Fimbriae, Bacterial,
pubmed-meshheading:11248232-Fimbriae Proteins,
pubmed-meshheading:11248232-Gene Expression Regulation, Bacterial,
pubmed-meshheading:11248232-Molecular Sequence Data,
pubmed-meshheading:11248232-Multigene Family,
pubmed-meshheading:11248232-Mutagenesis,
pubmed-meshheading:11248232-Polymerase Chain Reaction,
pubmed-meshheading:11248232-Pseudomonas aeruginosa,
pubmed-meshheading:11248232-Sequence Homology, Amino Acid,
pubmed-meshheading:11248232-Signal Transduction
|
| pubmed:year |
2001
|
| pubmed:articleTitle |
ctr1, a gene involved in a signal transduction pathway of the gliding motility in the cyanobacterium Synechocystis sp. PCC 6803.
|
| pubmed:affiliation |
Biomolecule Research Team, Korea Basic Science Institute, Taejon, South Korea.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|