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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2001-3-13
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pubmed:abstractText |
In both humans and rodents, males have lower levels of leptin than females at any level of adiposity. Experimental data support the idea that testosterone exerts a negative influence on leptin levels. There are, however, major inconsistencies in available data concerning the possible association between androgenicity and leptin in humans. Reasons could be the influence of androgenicity on leptin production being dependent on body composition, and incomplete measures of biologically active testosterone levels. In the present study we have characterized the relationship between biologically active testosterone and leptin after careful stratification for gender and adiposity.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0307-0565
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
98-105
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:11244464-Adipose Tissue,
pubmed-meshheading:11244464-Adult,
pubmed-meshheading:11244464-Aged,
pubmed-meshheading:11244464-Androstenedione,
pubmed-meshheading:11244464-Anthropometry,
pubmed-meshheading:11244464-Body Constitution,
pubmed-meshheading:11244464-Body Mass Index,
pubmed-meshheading:11244464-Cross-Sectional Studies,
pubmed-meshheading:11244464-Female,
pubmed-meshheading:11244464-Glucose Tolerance Test,
pubmed-meshheading:11244464-Humans,
pubmed-meshheading:11244464-Insulin,
pubmed-meshheading:11244464-Insulin-Like Growth Factor I,
pubmed-meshheading:11244464-Leptin,
pubmed-meshheading:11244464-Male,
pubmed-meshheading:11244464-Middle Aged,
pubmed-meshheading:11244464-Obesity,
pubmed-meshheading:11244464-Postmenopause,
pubmed-meshheading:11244464-Premenopause,
pubmed-meshheading:11244464-Radioimmunoassay,
pubmed-meshheading:11244464-Sex Characteristics,
pubmed-meshheading:11244464-Sex Hormone-Binding Globulin,
pubmed-meshheading:11244464-Testosterone
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pubmed:year |
2001
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pubmed:articleTitle |
A strong association between biologically active testosterone and leptin in non-obese men and women is lost with increasing (central) adiposity.
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pubmed:affiliation |
Department of Medicine, Umeå University Hospital, Umeå, Sweden. stefan.soderberg@medicin.umu.se
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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