rdf:type |
|
lifeskim:mentions |
umls-concept:C0015219,
umls-concept:C0017337,
umls-concept:C0031727,
umls-concept:C0085862,
umls-concept:C0205276,
umls-concept:C0282688,
umls-concept:C0441712,
umls-concept:C1123020,
umls-concept:C1299583,
umls-concept:C1335144,
umls-concept:C1511695,
umls-concept:C1549571,
umls-concept:C1608386,
umls-concept:C1708726
|
pubmed:issue |
3
|
pubmed:dateCreated |
2001-3-13
|
pubmed:databankReference |
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/G67176,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/G67177,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/G67178,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/G67179,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/G67180,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/G67181,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/G67182,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/G67183,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/G67184,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/G67185,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/G67186,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/G67187,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/G67188,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/G67190,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/G67191
|
pubmed:abstractText |
Hexaploid wheat is a young polyploid species and represents a good model to study mechanisms of gene evolution after polyploidization. Recent studies at the scale of the whole genome have suggested rapid genomic changes after polyploidization but so far the rearrangements that have occurred in terms of gene content and organization have not been analyzed at the microlevel in wheat. Here, we have isolated members of a receptor kinase (Lrk) gene family in hexaploid and diploid wheat, Aegilops tauschii, and barley (Hordeum vulgare). Phylogenetic analysis has allowed us to establish evolutionary relationships (orthology versus paralogy) between the different members of this gene family in wheat as well as with Lrk genes from barley. It also demonstrated that the sequences of the homoeologous Lrk genes evolved independently after polyploidization. In addition, we found evidence for gene loss during the evolution of wheat and barley. Analysis of large genomic fragments isolated from nonorthologous Lrk loci showed a high conservation of the gene content and gene organization at these loci on the homoeologous group 1 chromosomes of wheat and barley. Finally, sequence comparison of two paralogous fragments of chromosome 1B showed a large number of local events (sequence duplications, deletions, and insertions), which reveal rearrangements and mechanisms for genome enlargement at the microlevel.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/11244111-10393983,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11244111-10588718,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11244111-10607614,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11244111-10659785,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11244111-10688128,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11244111-10688139,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11244111-10838615,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11244111-10899971,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11244111-11016827,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11244111-11607556,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11244111-1715971,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11244111-2515110,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11244111-2762323,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11244111-3934395,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11244111-5449325,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11244111-7644483,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11244111-8978071,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11244111-9025301,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11244111-9383078,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11244111-9700067,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11244111-9796102
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pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0032-0889
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
125
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1304-13
|
pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:11244111-Base Sequence,
pubmed-meshheading:11244111-Chromosome Mapping,
pubmed-meshheading:11244111-DNA Primers,
pubmed-meshheading:11244111-Evolution, Molecular,
pubmed-meshheading:11244111-Genes, Plant,
pubmed-meshheading:11244111-Hordeum,
pubmed-meshheading:11244111-Molecular Sequence Data,
pubmed-meshheading:11244111-Phylogeny,
pubmed-meshheading:11244111-Polyploidy,
pubmed-meshheading:11244111-Receptor Protein-Tyrosine Kinases,
pubmed-meshheading:11244111-Triticum
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pubmed:year |
2001
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pubmed:articleTitle |
Molecular evolution of receptor-like kinase genes in hexaploid wheat. Independent evolution of orthologs after polyploidization and mechanisms of local rearrangements at paralogous loci.
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pubmed:affiliation |
Institute of Plant Biology, University of Zurich, CH-8008 Zurich, Switzerland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|