Linked Life Data

11239998

Source:http://linkedlifedata.com/resource/pubmed/id/11239998

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
2001-3-12
pubmed:abstractText
To determine if preloads of glucose act preabsorptively or postabsorptively to inhibit intake, 18-day-old rat pups were deprived for 24 h and then provided with sweet milk during a 30-min independent ingestion test. Five minutes before the test, gastric preloads (5% body weight, BW) or intraperitoneal injections (4 ml/kg BW) of isotonic, hypotonic, and hypertonic solutions of glucose or 2-deoxy-D-glucose (2-DG) were administered. There were two major results: First, preloads of 20% glucose decreased intake much more than intraperitoneal injections of 20% glucose. Second, a preload of 20% 2-DG, which decreases, rather than increases glucose utilization, was as effective as a preload of 20% glucose in decreasing intake. These results are consistent with a preabsorptive osmotic mechanism, but not with a postabsorptive metabolic mechanism, for mediating most, if not all, of the inhibition of intake 5 min after preloads of 20% glucose in rats on postnatal day 18 (P18).
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0031-9384
pubmed:author
pubmed:issnType
Print
pubmed:volume
72
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
199-203
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Hypertonic glucose preloads act preabsorptively to decrease intake in rats on postnatal day 18.
pubmed:affiliation
Developmental Psychobiology Laboratory, Department of Psychology, Bar Ilan University, Ramat Gan 52900, Israel.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't