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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2001-3-12
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pubmed:abstractText |
The HLA-DQB1 chain, in particular the amino acid in position 57, and genetic variants of the vitamin D-binding protein (DBP) have been reported to be associated with type 1 diabetes. There are two known polymorphisms in exon 11 of the DBP gene resulting in amino acid variants: codons 416 GAT --> GAG (Asp --> Glu) and 420 ACG --> AAG (Thr --> Lys). We compared distribution of DQB1 alleles and amino acid variants of DBP in type 1 diabetic patients (n = 44) in the Alsacian population and in healthy controls (n = 58).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0009-9120
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
59-63
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:11239517-Adolescent,
pubmed-meshheading:11239517-Adult,
pubmed-meshheading:11239517-Alleles,
pubmed-meshheading:11239517-Child,
pubmed-meshheading:11239517-Chromosomes, Human, Pair 4,
pubmed-meshheading:11239517-Codon,
pubmed-meshheading:11239517-Diabetes Mellitus, Type 1,
pubmed-meshheading:11239517-Exons,
pubmed-meshheading:11239517-Female,
pubmed-meshheading:11239517-France,
pubmed-meshheading:11239517-Gene Frequency,
pubmed-meshheading:11239517-Genotype,
pubmed-meshheading:11239517-HLA-DQ Antigens,
pubmed-meshheading:11239517-HLA-DQ beta-Chains,
pubmed-meshheading:11239517-Humans,
pubmed-meshheading:11239517-Male,
pubmed-meshheading:11239517-Polymorphism, Genetic,
pubmed-meshheading:11239517-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:11239517-Vitamin D-Binding Protein
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pubmed:year |
2001
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pubmed:articleTitle |
The HLA-DQB alleles and amino acid variants of the vitamin D-binding protein in diabetic patients in Alsace.
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pubmed:affiliation |
Centre Européen d'Etude du Diabète-Hôpitaux Universitaires de Strasbourg, 67000, Strasbourg, France. jean-claude.ongagna@wanadoo.fr
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pubmed:publicationType |
Journal Article
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