Source:http://linkedlifedata.com/resource/pubmed/id/11231124
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2001-3-20
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pubmed:abstractText |
The life cycle of most eukaryotic organisms includes a meiotic phase, in which diploid parental cells produce haploid gametes. During meiosis a single round of DNA replication is followed by two rounds of chromosome segregation. In the first, or reductional, division (meiosis I), which is unique to meiotic cells, homologous chromosomes segregate from one another, whereas in the second, or equational, division (Meiosis II) sister centromeres disjoin. Meiotic DNA replication precedes the initiation of recombination by programmed Spo11-dependent DNA double-strand breaks. Recent reports that meiosis-specific cohesion is established during meiotic S phase and that the length of S phase is modified by recombination factors (Spo11 and Rec8) raise the possibility that replication plays a fundamental role in the recombination process.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/CLB5 protein, S cerevisiae,
http://linkedlifedata.com/resource/pubmed/chemical/CLB6 protein, S cerevisiae,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclin B,
http://linkedlifedata.com/resource/pubmed/chemical/Fungal Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Saccharomyces cerevisiae Proteins
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0960-9822
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
23
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
88-97
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pubmed:dateRevised |
2008-10-31
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pubmed:meshHeading |
pubmed-meshheading:11231124-Cyclin B,
pubmed-meshheading:11231124-Fungal Proteins,
pubmed-meshheading:11231124-Meiosis,
pubmed-meshheading:11231124-Recombination, Genetic,
pubmed-meshheading:11231124-Saccharomyces cerevisiae,
pubmed-meshheading:11231124-Saccharomyces cerevisiae Proteins,
pubmed-meshheading:11231124-Synaptonemal Complex
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pubmed:year |
2001
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pubmed:articleTitle |
B-type cyclins CLB5 and CLB6 control the initiation of recombination and synaptonemal complex formation in yeast meiosis.
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pubmed:affiliation |
Institut Curie, Section de Recherche, CNRS-UMR144 Cedex 05 75248, Paris, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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